Hair loss remains a prevalent concern globally, affecting both men and women across various age groups. In India, the demand for effective and non-invasive treatments has led to the rise of Platelet-Rich Plasma (PRP) therapy as a promising solution.

A 2024 meta-analysis of randomised controlled trials revealed a significant increase in hair density among patients undergoing PRP therapy for androgenetic alopecia, with a mean difference of 25.09 hairs/cm². This highlights the potential of PRP in effectively treating pattern baldness, though variability in success rates underscores the importance of personalised treatment plans tailored to individual needs.

PRP is a minimally invasive procedure with minimal downtime, making it an attractive option for those seeking alternatives to surgical hair restoration methods. This article explores the mechanisms of PRP therapy, its effectiveness, potential side effects, and provides practical tips for individuals considering this treatment for hair loss.

What is PRP Hair Treatment?

PRP (Platelet-Rich Plasma) hair treatment is a regenerative therapy designed to stimulate and promote healthy hair growth. It uses your blood to concentrate platelets and growth factors, which are then injected into areas of thinning or balding hair to encourage regrowth.

Here’s how PRP works:

• Blood Collection: A small sample of your blood is drawn, typically from your arm.
• Platelet Concentration: The blood is processed in a centrifuge to separate and concentrate platelets and growth factors.
• Injection: The platelet-rich plasma is injected into the scalp, targeting areas with thinning hair to stimulate follicle activity.
• Hair Follicle Stimulation: The growth factors in PRP activate dormant hair follicles, increase blood flow to the scalp, and prolong the hair growth phase, resulting in thicker, healthier hair over time.

Key Mechanisms of PRP Hair Treatment:

Here’s how PRP works to stimulate hair growth and improve follicle health.

• Activation of Dormant Follicles: PRP rejuvenates hair follicles that have entered a resting phase, stimulating them to re-enter the growth phase (anagen). This can aid in hair regrowth, particularly in cases of early hair loss or thinning.
• Improved Scalp Blood Flow: The injection of PRP promotes better blood circulation in the scalp, ensuring that hair follicles receive optimal nutrients and oxygen to function efficiently.
• Stimulation of Tissue Repair and Regeneration: The growth factors present in PRP encourage the natural healing process of the scalp, repairing damaged tissues and enhancing overall scalp health. This creates a conducive environment for hair growth.

PRP is most effective in cases of early-stage hair thinning or loss, including conditions such as telogen effluvium (a condition triggered by stress or shock that causes excessive hair shedding). It can also serve as a follow-up treatment after a hair transplant. 

Step-by-Step Process of the PRP Hair Treatment

The PRP (Platelet-Rich Plasma) hair treatment involves a series of well-defined steps designed to maximise hair regrowth by utilising your body’s healing properties. Here’s a detailed look at the procedure:

Step 1. Blood Collection: The procedure begins with a blood draw from your arm, similar to any standard blood test. The amount of blood taken is minimal, typically around 10-20 millilitres, and the process is quick and straightforward.

Step 2. Centrifugation: Once the blood is collected, it is placed in a centrifuge, a specialised machine that spins the blood at high speeds. This process separates the blood components, isolating the platelet-rich plasma (PRP) from the other elements, such as red and white blood cells. The result is a concentration of platelets, growth factors, and proteins that promote healing and regeneration.

Step 3. Injection: The concentrated PRP is then carefully injected into the scalp using fine, sterile needles. The injections are strategically administered to areas of hair thinning or loss, targeting the follicles to stimulate hair growth. The number of injections depends on the extent of hair loss and the areas that require treatment.

Session Details:

Here’s what to expect during and after each session:

• Duration: Each PRP session typically lasts between 45 and 60 minutes, including both the blood collection and the PRP injection phases. The procedure is relatively quick and is performed in a clinical setting.
• Number of Sessions: To achieve optimal results, most patients require 4 to 6 sessions. These sessions are spaced 4 to 6 weeks apart, allowing sufficient time for the scalp to respond to the treatment before the next round of injections. The exact number of sessions needed may vary depending on individual goals and the extent of hair loss.
• Downtime: One of the significant advantages of PRP hair treatment is the minimal downtime. Most patients can resume their normal daily activities immediately following the procedure. There may be slight redness or swelling at the injection sites, but this typically resolves within a few hours to a day. There is no need for anaesthesia, and no stitches are required, making it a non-invasive option for those seeking hair restoration.

Are you considering hair restoration treatments? Book a consultation for PRP/GFC Hair Therapy at Velantis Dermatology. Every treatment is doctor-led and evidence-based, ensuring the best possible results for your hair growth journey.

Who is an Ideal Candidate for PRP Hair Treatment?

PRP hair treatment is an effective option for individuals experiencing various types of hair loss. It is particularly beneficial for both men and women who are in the early stages of hair thinning or loss. The following conditions make someone an ideal candidate for PRP therapy:

• Early-Stage Androgenetic Alopecia: Also known as male or female pattern baldness, this condition typically results in a gradual thinning of hair. PRP can help stimulate the dormant hair follicles and encourage regrowth in areas where thinning is evident.
• Telogen Effluvium: This type of hair loss is often triggered by stress, trauma, or a significant life event. PRP can help revitalise hair growth by stimulating the scalp and activating dormant follicles.
• Hair Thinning After Illness: Conditions like illness-induced hair loss can lead to noticeable thinning. PRP has shown effectiveness in restoring hair density by rejuvenating weakened follicles.
• Maintenance After a Hair Transplant: PRP can complement hair transplant procedures by stimulating newly transplanted follicles, improving their chances of long-term success, and promoting overall scalp health.
• General Thinning Without Complete Bald Patches: Individuals who experience gradual thinning across their scalp, but have not yet developed complete bald patches, may benefit from PRP to restore hair density and prevent further loss.

Who is It Not Recommended For? 

However, PRP hair treatment is not suitable for everyone. It is generally not recommended for:

• Individuals with Chronic Liver Disease: PRP relies on the ability to process platelets and growth factors, which may be compromised in those with liver conditions.
• Platelet Disorders: Conditions that affect platelet function can hinder the effectiveness of PRP therapy.
• Active Scalp Infections: Any existing scalp infection must be treated and resolved before starting PRP, as the treatment may exacerbate the condition.
• Those on Anticoagulant Therapy: Blood thinners can interfere with the platelet collection and may lead to complications during treatment.
• Pregnant or Breastfeeding Women: Due to potential hormonal changes and safety concerns, PRP is generally not recommended during pregnancy or while breastfeeding.

Effects and Expected Results of PRP Hair Treatment

Understanding what PRP can realistically achieve helps patients make informed decisions and track their progress over time.

What to Expect?

Patients can look forward to several improvements as the treatment progresses:

• Enhanced hair density and thickness, with many patients observing a fuller appearance in treated areas.
• A noticeable reduction in daily hair shedding often occurs within the first few sessions.
• Enhanced scalp coverage, resulting in a healthier overall appearance.

Timeline for Results

The benefits of PRP do not appear overnight. Here is what most patients can anticipate:

Note: Individual responses vary depending on the cause and extent of hair loss, age, underlying health conditions, and adherence to the treatment schedule. Maintenance sessions may be recommended to sustain results.

Success Rate:

Clinical studies in India report that 84–95% of patients with androgenetic alopecia experience measurable improvements in hair density and scalp coverage following PRP, especially when combined with medical management and appropriate aftercare.

PRP hair therapy offers a scientifically supported option for those with early or moderate hair thinning, provided treatment is customised to the patient’s specific needs and medical background.

Tips for Maximising PRP Results

To ensure optimal outcomes from your PRP hair treatment, following these guidelines before, after, and in the long term will help enhance the effects and maintain the health of your hair.

Before Your Session

To prepare for your PRP hair treatment and ensure optimal results, follow these guidelines in the days leading up to your appointment.

• Avoid Anti-Inflammatory Medications: Certain medications, such as ibuprofen or aspirin, can interfere with platelet function. It's advised to stop taking these for at least a week before your session to avoid compromising the treatment's effectiveness.
• Stay Hydrated: Drinking plenty of water before your session helps improve blood circulation, allowing the PRP to be extracted more effectively.
• Eat a Light Meal: Consuming a light meal before your appointment can help stabilise your blood sugar levels, preventing dizziness or discomfort during the procedure.

After Your Session

Proper aftercare is crucial to maximise the benefits of PRP therapy and ensure a smooth recovery. Follow these tips to help maintain your results.

• Do Not Wash Your Hair for 24 Hours: This helps protect the scalp and allows the PRP to settle into the treated areas. Washing your hair too soon can reduce the efficacy of the treatment.
• Avoid Direct Sun Exposure: After the procedure, your scalp may be sensitive to sunlight. It's essential to avoid exposing your scalp to direct sunlight for at least 48 hours to prevent irritation or complications.
• Refrain from Strenuous Exercise: Intense physical activity can increase blood flow to the scalp, potentially compromising the effectiveness of the PRP. Avoid strenuous exercise for 24 to 48 hours after treatment.

Long-Term Maintenance

Maintaining your results requires consistent care and attention. These long-term strategies will help you keep the benefits of your PRP treatment and support ongoing hair health.

• Follow Your Dermatologist’s Maintenance Schedule: For optimal results, it is recommended that you follow up with your dermatologist every 4 to 6 months. These sessions help maintain the progress made during the initial course of treatment and ensure long-term results.
• Use Prescribed Medications: If your dermatologist has recommended any topical or oral medications, follow their instructions carefully. These can work more effectively in conjunction with PRP therapy to further enhance hair growth.
• Maintain a Healthy Diet and Manage Stress: A balanced diet rich in essential vitamins and minerals is crucial for maintaining hair health. Additionally, managing stress levels can reduce the risk of hair loss and support the ongoing health of your follicles.

Benefits and Risks of PRP Hair Treatment

PRP (Platelet-Rich Plasma) hair treatment offers a range of benefits, making it a popular choice for individuals looking to address hair loss without undergoing surgery. However, as with any medical procedure, it is important to understand both the benefits and the potential risks before proceeding.

1. Non-Surgical and Minimally Invasive

PRP therapy does not require any incisions or stitches, making it a non-invasive option for hair restoration. The procedure is quick, with minimal discomfort and no need for anaesthesia, which reduces the risk of complications.

2. Low Risk of Allergic Reactions

Because PRP uses your blood, the risk of allergic reactions or side effects is significantly reduced. This makes it a safer option compared to treatments involving synthetic compounds or foreign substances.

3. Quick Recovery 

One of the key advantages of PRP hair treatment is the minimal downtime. Most patients can resume their normal activities, including returning to work, immediately after the procedure. The recovery process is generally smooth, with no significant disruptions to daily routines.

4. Versatile 

PRP treatment can be combined with other therapies such as minoxidil, finasteride, or microneedling to enhance results. This flexibility allows for a personalised approach to hair restoration, catering to individual needs and the severity of hair loss.

5. Suitable for Both Men and Women 

PRP therapy is effective for both men and women, addressing a range of hair loss conditions, including male and female pattern baldness, stress-induced hair thinning, and post-illness hair loss.

While PRP offers numerous benefits, it is essential to be aware of the potential risks and side effects that can occur during and after the procedure.

Risks, Side Effects, and Recovery

While PRP hair treatment is generally considered safe, it is essential to be aware of some potential side effects and risks. Understanding these will help manage expectations and ensure a smooth recovery process.

Common Side Effects:

These side effects are typically mild and temporary, but it's essential to know what to expect during the recovery period.

• Mild Redness, Swelling, or Tenderness at Injection Sites: These are common and typically resolve within 24 to 48 hours after the procedure. The discomfort is usually minimal and temporary.
• Temporary Scalp Sensitivity: Some patients may experience mild sensitivity in the treated areas for a few days, but this is generally short-lived.

Rare Risks:

Although rare, some risks can still occur. Being aware of these ensures you're prepared should they arise.

• Infection: Although rare, there is a slight risk of infection. However, this is highly unlikely when the procedure is performed by a qualified dermatologist using sterile equipment.
• Bruising or Mild Bleeding: Some patients may notice bruising or mild bleeding at the injection sites, but these symptoms typically resolve quickly.

Recovery Tips:

Following proper aftercare is crucial for achieving optimal results and preventing complications. Here are a few recovery guidelines to follow:

• Avoid Washing Your Hair for 24 Hours: It is recommended to refrain from washing your hair for at least 24 hours after the procedure to prevent irritation and allow your scalp to settle.
• Refrain from Vigorous Exercise: Avoid activities that may cause excessive sweating or pressure on the treated areas, such as strenuous exercise or scalp massage, for 48 hours post-treatment.
• Follow Your Dermatologist’s Aftercare Instructions: Adhering to the specific aftercare instructions provided by your dermatologist will ensure optimal results and minimise any risks of complications.

Cost of PRP Hair Treatment in Chennai

Several factors influence the cost of PRP hair treatment in Chennai, each contributing to the overall investment required for effective therapy. Patients should consider not only the price per session but also the quality and safety standards of the clinic they choose to visit.

Average Cost per Session

In Chennai, a single session of PRP hair treatment typically ranges from ₹4,000 to ₹11,000. This variation reflects differences in clinic reputation, the expertise of the treating dermatologist, and the technology or protocols employed during the procedure.

Key Factors Affecting Cost

The cost of PRP hair treatment depends on several factors that can influence the number of sessions required.

• Severity and Area of Hair Loss: Larger areas or more advanced hair thinning may require additional sessions, which can increase the total expense.
• Number of Sessions Required: Most patients need multiple sessions, often spaced a month apart, to achieve and maintain optimal results.
• Experience of the Dermatologist: Clinics led by board-certified dermatologists or those with extensive experience may charge higher fees, reflecting their expertise and commitment to safety.
• Quality of Equipment and Protocols: The use of advanced centrifuges, adherence to sterile techniques, and strict adherence to evidence-based protocols can influence the cost while also enhancing treatment outcomes.

When considering PRP therapy, it is advisable to prioritise clinical standards and practitioner qualifications over the lowest price. Transparent pricing, clear communication about the number of sessions needed, and a focus on patient safety are hallmarks of reputable clinics in Chennai.

Explore safe and affordable PRP hair growth treatment at Velantis Dermatology: transparent pricing, no upselling, and doctor-led care. Book your appointment today.

Wrapping Up

PRP hair treatment provides a clinically proven, minimally invasive solution for hair loss. With its high success rate, low risk, and ability to complement other therapies, it has become a cornerstone in modern hair restoration.

Velantis Dermatology prioritises medical precision and ethical care, ensuring each treatment plan is personalised to achieve the best possible results for long-term patient satisfaction. Founded by Dr. Janani (MD, Dermatologist), our clinic is dedicated to providing safe, evidence-based treatments for hair loss and other dermatological concerns in Chennai.

If you’re considering a personalised hair restoration treatment plan, our team of expert dermatologists is ready to guide you. We offer comprehensive consultations and practical solutions, always with a focus on your health, appearance, and confidence.

Book your consultation for Hair Restoration, Hair Loss Treatment, or PRP/GFC Hair Therapy at Velantis Dermatology, Chennai, where science, safety, and self-confidence meet.

FAQs

Q1. How does lifestyle impact the effectiveness of PRP hair treatment?
A1. Lifestyle factors like diet, stress levels, sleep quality, and smoking can significantly influence the results of PRP therapy. A balanced diet rich in proteins, vitamins, and minerals supports hair follicle health, while chronic stress and poor sleep may hinder the regenerative effects of PRP. Smoking, in particular, impairs blood flow and can reduce the treatment’s efficacy by limiting nutrient delivery to the scalp.

Q2. Are there any specific pre-treatment preparations recommended for PRP hair therapy?
A2. Before undergoing PRP treatment, patients are usually advised to avoid anti-inflammatory medications and supplements that may affect platelet function for several days. Staying well-hydrated and eating a healthy meal before the session can help minimise dizziness or discomfort during the blood draw. It’s also important to disclose any recent illnesses or changes in medication to your dermatologist for safe and optimal results.

Q3. What role does genetics play in the success of PRP hair treatment?
A3. Genetics largely determines how hair follicles respond to PRP therapy. Individuals with a strong family history of androgenetic alopecia may experience slower or less pronounced improvements compared to those with non-genetic causes of hair loss. While PRP can stimulate dormant follicles, it cannot reverse genetic predispositions, so expectations should be discussed with a specialist.

Q4. Can PRP hair treatment be safely repeated over many years?
A4. Current evidence suggests that PRP is safe for repeated use, as it utilises the patient’s blood components and does not introduce foreign substances. Many patients opt for maintenance sessions every 6 to 12 months to maintain their results. Long-term safety is supported by clinical experience, but ongoing research continues to monitor for any rare or cumulative side effects.

Q5. How do environmental factors, like pollution and hard water, affect PRP outcomes?
A5. Environmental stressors such as air pollution and hard water can weaken hair shafts and irritate the scalp, potentially reducing the overall benefits of PRP. Patients living in highly polluted areas or using hard water are encouraged to adopt protective hair care routines and consult their dermatologist about additional scalp treatments to maximise and maintain the gains from PRP therapy.

Q6. Does PRP treatment actually work?
A6. PRP hair treatment has shown positive results for many individuals, particularly in cases of early hair thinning or loss. By stimulating dormant hair follicles and enhancing blood circulation to the scalp, PRP can help improve hair density and thickness. However, its effectiveness can vary depending on the individual’s hair loss condition, genetics, and consistency in following treatment protocols.

Q7. How many sessions do I need for PRP hair treatment?
A7. The number of PRP sessions needed varies from person to person. Generally, 3 to 4 sessions spaced 4 to 6 weeks apart are recommended to see noticeable improvements. Maintenance sessions, usually every 6 to 12 months, can help maintain the results. Your dermatologist will assess your progress and recommend a treatment plan based on your specific needs.

Q8. Is PRP hair treatment permanent?
A8. While PRP hair treatment can offer long-lasting results, it is not a permanent solution. PRP works by rejuvenating hair follicles and stimulating growth, but natural ageing and ongoing factors like genetics, stress, or poor nutrition can affect hair health over time. To maintain results, periodic maintenance treatments are advised.